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how to get slime out of clothes, To remove slime from clothes, first let the slime dry. Once it’s dry, gently scrape off as much as possible with a blunt knife or the edge of a credit card. Apply a pre-treatment stain remover or a mixture of warm water and dish soap to the stain. Gently rub the fabric together, then launder the clothing as usual. Check the stain before drying, and repeat the process if necessary.